人物履历
2007毕业于中国科学技术大学获得理学博士学位;2007年至2011年于瑞士Ludwig肿瘤学研究所从事博士后研究。主要研究成果发表于PNAS,Blood和JIMMUNOL等国际高水平杂志。
获得荣誉
获2006年中科院院长优秀奖和2007年中华医学会一等奖。
2018年9月30日,获得第三届北京市华侨华人“京华奖”。
研究领域
1)肠道上皮内淋巴细胞功能及发育分化研究
2)模式识别受体调节肠道粘膜稳态的机制研究
代表论著
1、
Jiang W
, Sun R, Wei H, Tian Z. Toll-like receptor 3 ligand attenuates LPS-induced liver injury by down-regulation of toll-like receptor 4 expression on macrophages. Proc. Natl. Acad. Sci. USA (PNAS)
2005, 102(47): 17077–17082.2、
Jiang W
, Ferrero I, Laurenti E, Trumpp A, Macdonald HR. c-Myc controls the development of CD8αα TCRαβ intestinal intraepithelial lymphocytes from thymic precursors by regulating IL-15-dependent survival. Blood
. 2010, 115(22):4431-8.3、
Jiang W
, Sun R, Zhou R, Wei H, Tian Z. TLR-9 activation aggravates concanavalin A-induced hepatitis via promoting accumulation and activation of liver CD4+ NKT cells. J Immunol
. 2009,182(6):3768-74.4、Fiorini E, Merck E, Wilson A, Ferrero I,
Jiang W
, Koch U, Auderset F, Laurenti E, Tacchini-Cottier F, Pierres M, Radtke F, Luther SA, Macdonald HR. Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies. J Immunol
. 2009, 183(11):7212-22.5、Mycko MP, Ferrero I, Wilson A,
Jiang W
, Bianchi T, Trumpp A, MacDonald HR. Selective requirement for c-Myc at an early stage of Vα14i NKT cell development. J Immunol
. 2009, 182(8):4641-8.6、Chen Y, Sun R,
Jiang W
, Wei H, Tian Z. Liver-specific HBsAg transgenic mice are over-sensitive to Poly (I:C)-induced liver injury in NK cell- and IFN-γ denpendent manner. 2007, 47(2):183-90.