scien domain calmodulin

性别

女

国籍

中国

人物简介

姓名：曹又佳

性别：女

职称：教授

所属部门：生物化学和分子生物学系

研究方向：T细胞激活与凋亡信号转导机制；病毒蛋白与宿主免疫分子作用机制

南开大学生命科学学院教授

1987年获得南开大学学士学位； 1994于美国印第安纳大学医学院获得生物化学博士学位。1994-1995于美国华盛顿大学做博士后；1995年受聘于美国Avantis制药公司任Sr.Research scientist；1998-2001年于杜克大学从事癌症与免疫T细胞信号转导研究；2002年回国至今为南开大学特聘教授、博士生导师；天津市特聘教授，教育部新世纪优秀人才获得者。

主要学术论文

1.周卓，尹洁，窦植洵，唐钧，张翠竹，曹又佳. The calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes. JOURNAL OF BIOLOGICAL CHEMISTRY 282-32-23737-23744. 2007-1-1

2.贾云芳; 秦 明; 张宏凯; 牛文成; 李 萧; 王立凯; 李 欣; 白云鹏; 曹又佳；冯喜增* . Label-free biosensor: A novel phage-modified light addressable potentiometric sensor system for cancer cell monitoring. BIOSENSORS & BIOELECTRONICS 22-12-3261-3266. 2007-1-1

3.张翠竹，唐钧，谢佳，张宏恺，李亚鹏，张杰，Verpooten D，何斌，曹又佳. A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalia. FEBS Lett. 582--171-176 . 2008-1-23

4.Guo Y, Rumschlag-Booms E, Wang J, Xiao H, Yu J, Wang J, Guo L, Gao GF, Cao Y, Caffrey M, Rong L. Analysis of hemagglutinin-mediated entry tropism of H5N1 avian influenza.. Virology Journal 6-39-1-13. 2009-4-1

5.Hongkai Zhang， Xin Li，Yunpeng Bai，Ruifang Niu，Yunfang Jia，Cuizhu Zhang，Lin Zhang，Xizeng Feng and Youjia Cao. Metastatic cell detection using a phage peptide modified light addressable potentiometric sensor. Biotechnol. Appl. Biochem. 53-3-185-192. 2009-7-1

6.Verpooten D, Feng Z, Valyi-Nagy T, Ma Y, Jin H, Yan Z, Zhang C, Cao Y, He B. Dephosphorylation of eIF2{alpha} Mediated by the {gamma}134.5 Protein of Herpes Simplex Virus 1 Facilitates Viral Neuroinvasion.. JOURNAL OF VIROLOGY, 83-23-12626–12630. 2009-12-1

7.Jin H, Ma Y, Prabhakar BS, Feng Z, Valyi-Nagy T, Yan Z, Verpooten D, Zhang C, Cao Y, He B. The gamma 1 34.5 protein of herpes simplex virus 1 is required to interfere with dendritic cell maturation during productive infection.. Journal of Virology 83-10-4984-4994. 2009-5-1

8.Miao Guo, Yu Yan, Hongkai Zhang, Husheng Yan, Youjia Cao, Keliang Liu, Shourong Wan, Junsheng Huang and Wei Yue. Magnetic and pH-responsive nanocarriers with multilayer core–shell architecture for anticancer drug . Journal of Materials Chemistry 18--5104-5112. 2008-9-1

9.Cao, Y., Janssen, E.M., Duncan, A. W., Altman,A., Billadeau,D.D., and Abraham, R.T. . Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line. EMBO J. 21-18-4809-4819. 2002-9-16