人物经历
1992-1996中国科学技术大学 化学物理系 本科
1997-2000中国科学技术大学 化学系 硕士
2000-2002美国Wayne State University,博士(转学)
2002-2007美国The Ohio State University,化学博士
2007-2008 美国The Ohio State University,博士后
2009-至今南开大学药学院 副教授
其他作品
主要研究对象:抗癌类药物的合成和设计;所研究过的药物分子包括:rebeccamycin analogs,anthracycline analogs,HDACi,geldanamycin analogs 和GST-targeting drugs
发表论文| 1 Shen, J.; Woodward, R.; Kedenburg, J. P.; Liu, X.; Chen, M. Histone Deacetylase Inhibitor through Click Chemistry. J. Med. Chem. 2008, 51(23), 7417-7427. |
| 2 Li, M.; Shen, J.; Liu, X.; Shao, J.; Yi, W.; Chow, C. S.; Wang, P. G. Identification of a New a 1,2-Fucosyltransferase Involved in O-Antigen Biosynthesis of Escherichia coli O86:B7 and Formation of H-Type 3 Blood Group Antigen. Biochemistry, 2008,47(44), 11590-11597。 |
| 3 Yi, W.; Shen, J.; Zhou, G.; Li, J.; Wang, P. G. Bacterial Homologue of Human Blood Group A Transferase. Journal of the American Chemical Society 2008, 130(44), 14420-14421. |
| 4 Li, M.; Liu, X.; Shao, J.; Shen, J.; Jia, Q.; Yi, W.; Song, J. K.; Woodward, R.; Chow, C. S.; Wang, P. G. Characterization of a Novel a 1,2-Fucosyltransferase of Escherichia coli O128:B12 and Functional Investigation of Its Common Motif. Biochemistry, 2008, 47(1), 378-387. |
| 5 Cui, H.; Shen, J.; Lu, D.; Zhang, T.; Zhang, W.; Sun, D.; Wang, P. G. 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer Chemotherapy and Pharmacology, 2008, 62(3), 509-515. |
| 6 Battisti RF, Zhong Y, Fang L, Gibbs S, Shen J, Nadas J, Zhang G, Sun D. “Modifying the Sugar Moieties of Daunorubicin Overcomes P-gp-Mediated Multidrug Resistance”. Molecular Pharmaceutics, 2007, 4,140-153. |
展开表格申请专利| 点击化学合成具有分支结构的组蛋白去乙酰化酶抑制剂,王鹏,沈杰,尹正. |