李娜（北京大学教授）

人物经历

1994-1998年，北京大学化学学院工作。

1999-2000年，美国堪萨斯大学药化系CDDR博士后。

2000年，北京大学化学学院工作。

主要成就

研究领域和兴趣

主要研究方向为光学传感新原理、新方法。

光学传感新原理、新方法。主要兴趣为：基于金属纳米材料光谱（荧光、局域表面等离子体共振吸收/散射）的生物传感，以及生物大分子与小分子的相互作用。

具有纳米层间结构固定相的合成、酶及其他分子的固定化及其应用于分离以及光学传感器的研究等。生物大分子（蛋白质，核酸，糖类物质等）与小分子的超分子作用及其在生物大分子测定方面的应用研究。

口腔保健产品临床功能的实验室评价方法的建立及实施，如牙膏和洁牙剂的摩擦力及物理和化学清洁力的国际标准的建立和评价，与龋齿病相关的牙釉质脱矿和再矿化程度的定量测定方法的建立等。临床数据的统计处理。

著作

1. Quantitative Chemical Analysis(英文).北京大学出版社，2009(主编)（海外发行World Scientific Publishing Co Pte Ltd,2013）。
2. 分析化学I（电子课件）.北京大学出版社,2007(主编)。
3. 分析化学教程学习指导.北京大学出版社,2006(参编)。
4. 分析化学教程.北京大学出版社,2005(参编)。
5. 超越分子前沿.科学出版社，2004(参译)。
6. 2011年北京市高等教育精品教材。

论文

1. Tian Li, Xi Wu, Guangyu Tao, Haoyan Yin, Junlong Zhang, Feng Liu,

Na Li*

A simple and non-amplification platform for femtomolar DNA and microRNA detection by combining automatic gold nanoparticle enumeration with target-induced strand-displacement.

Biosens. Bioelectron.

 2018

2. Xiaojing Pei, Tiancheng Lai, Guangyu Tao, Hu Hong, Feng Liu,

Na Li*

Ultra-specific multiplexeddetection of low-abundance single-nucleotide variants by combining masking tactic with fluorescent nanoparticle counting.

Anal. Chem.

2018

3. Xiaojing Pei, Haoyan Yin, Tiancheng Lai, Junlong Zhang, Feng Liu,

 Xiao Xu

Na Li*

Multiplexed Detection of Attomole Nucleic Acids Using Fluorescent Nanoparticle Counting Platform

Anal. Chem.

2018

4. Guangyu Tao, Yang Chen, Ruoyun Lin, Jiang Zhou, Xiaojing Pei, Feng Liu,

Na Li

How G-quadruplex topology and loop sequences affect optical properties of DNA-templated silver nanoclusters

Nano Res.

2017

5. Ruoyun Lin, Guangyu Tao, Yang Chen, Mingxing Chen, Feng Liu,

Na Li*

Constructing a robust fluorescent DNA-stabilized silver nanocluster probe module by attaching a duplex moiety

Chem. Eur. J.

2017

6. Runyun Lin, Chenxi Li, Yang Chen, Feng Liu,

Na Li*

Metal-enhanced fluorescence in biosensing applications, "Surface Plasmon Enhanced, Coupled and Controlled Fluorescence",

2017

7. Wu, Xi, Tian Li, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu,

Na Li

Universal and Enzyme-Free Immunoassay Platform for Biomarker Detection Based on Gold Nanoparticle Enumeration with a Dark-Field Microscope.

Analyst,

2017

8. Tian Li, Xi Wu, Feng Liu,

Na Li*

Analytical Methods Based on the Light-Scattering of Plasmonic Nanoparticles at the Single Particle Level with Dark-Field Microscopy Imaging.

Analyst,

2017

9. Chenxi Li, Yixin Li, Yang Chen, Ruoyun Lin, Tian Li, Feng Liu,

Na Li*

Modulating the DNA strand-displacement kinetics with the one-sided remote toehold design for differentiation of single-base mismatched DNA.

RSC Adv.

 2016

10. Yang Chen, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu,

 Na Li*

Pre-Incubation of Auric Acid with DNA Is Unnecessary for the Formation of DNA-Templated Gold Nanoclusters

Chem.-an Asian J.

2016

11. Tian Li, Xiao Xu, Guoqing Zhang, Ruoyun Lin, Yang Chen, Chenxi Li, Feng Liu,

 Na Li*

Nonamplification Sandwich Assay Platform for Sensitive Nucleic Acid Detection Based on Aunps Enumeration with the Dark-Field Microscope

Anal. Chem.

 2016

12. Xiao Xu, Tian Li, Zhongxing Xu, Hejia Wei, Ruoyun Lin, Bin Xia, Feng Liu,

 Na Li*

Automatic enumeration of gold nanomaterials at single particle level

Anal. Chem.

2015

13. Hongduan Huang, Hejia Wei, Mingjian Zou, Xiao Xu,

 Bin Xia

 Na Li*

Modulating fluorescence anisotropy of terminally labeled dsDNA via the interaction between dye and nucleotides for rational design of DNA-recognition based applications

Anal. Chem.

2015

14. Zhenpeng Zhou, Tian Li, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,*

Na Li*

A dual amplification strategy for DNA detection combining bio-barcode assay and metal-enhanced fluorescence modality.

Chem. Commun.

2014

15. Chenxi Li, Yixin Li, Xiao Xu, Xinyi Wang, Yang Chen, Xiaoda Yang, Feng Liu,

 Na Li*

Fast and quantitative differentiation of single-base mismatched DNA by initial reaction rate of catalytic hairpin assembly.

Biosens. Bioelectron.

2014,

16. Zhenpeng Zhou, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,

 Na Li*

A distance-dependent metal-enhanced fluorescence sensing platform based on molecular beacon design

Biosens. Bioelectron.

 2014

17. Xinyi Wang, Mingjian Zou, Hongduan Huang, Yuqian Ren, Limei Li, Xiaoda Yang,

 Na Li

Gold nanoparticle enhanced fluorescence anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction

Biosens. Bioelectron.

2013

18. Xiao Xu, Yang Chen, Hejia Wei, Bin Xia, Feng Liu

, Na Li

Counting Bacteria Using Functionalized Gold Nanoparticles as the Light-Scattering Reporter

Anal. Chem.

2012

19. Mingjian Zou, Yang Chen, Xiao Xu, Hongduan Huang, Feng Liu,

Na Li

The homogeneous Fluorescence Anisotropic Sensing of Salivary Lysozyme Using the 6-carboxy fluorescein-labeled DNA Aptamer.

Biosens. Bioelectron.

2012

从1994年参加分析化学实验、仪器分析实验、高等分析实验教学，以及定量化学分析课教学。现主讲定量化学分析。^[1]

获得荣誉