人物履历
1982年毕业于山东农业大学;
先后获山东农业大学农学硕士和中国农业大学理学博士学位;
1989年2月至6月赴丹麦哥本哈根研修种子技术;
1992年1月至1996年1月赴美国加利福尼亚大学戴维斯分校植物生物学系留学,主要从事植物分子生物学方面的研究;
2001年作为教育部选派的高级访问学者赴美国北卡罗莱纳大学合作研究,主要进行了转基因表达调控的研究。
中国共产党山东省第十一届委员会委员。
任免信息
2018年6月24日,中国共产党山东省第十一届委员会第五次全体会议通过,决定递补十一届省委候补委员郑成超同志为十一届省委委员。[1]
学术兼职
山东生物化学与分子生物学学会副理事长
《植物学报》编委
《农业生物技术学报》编委
所获荣誉
2004年入选国家“
新世纪
百千万人才工程”国家级人才[2];2007年入选
教育部“长江学者创新团队
”带头人;泰山学者特聘教授
2008年入选
有突出贡献的中青年专家
;1996年,获山东省“青春立功”一等功;
山东省新长征突击手称号。
科研项目
主持承担了国家“
863
”、国家“ 973
”、国家转基因植物研究专项
、国家自然科学基金、教育部博士点科研基金
等多项课题。
郑成超
1、国家转基因植物研究专项《植物叶片高效特异表达启动子及 表达载体的研制》;2、国家“863”计划项目《棉花耐盐基因的分离、功能鉴定与应用》;
3、国家“973”计划项目《作物应答高盐、低温胁迫的分子调控机理》;
4、国家自然科学基金《PNZIP基因的生物学功能鉴定与分析》;
5、国家自然科学基金《拟南芥转录因子AT103突变体分离及其功能研究》;
6、国家自然科学基金《一个新型棉花CCCH锌指转录因子的功能鉴定与分析》;
7、教育部“长江学者创新团队发展计划”《作物高产优质的生理与分子基础》2007-2009;
8、国家转基因专项《作物抗除草剂抗逆基因克隆》1998-2003;
9、国家自然科学基金《拟南芥miRNA169家族及靶基因的功能鉴定与分析》2010-2013
申请专利
在重要功能基因、特异启动子克隆与功能鉴定等方面均获得了许多拥有我国自主知识产权的研究成果,申请专利8项
注册基因
克隆并在GenBank注册基因36个。
教学工作
主讲
本科生《Gene cloning and DNA analysis》、《基因工程实验》;
硕士生《生物化学与分子生物学专业英语》;
博士生《生物化学与分子生物学专题讨论》;
招收生物学博士后。
研究方向
1.植物重要功能基因的克隆、鉴定与利用:
以重要农作物小麦、玉米、棉花、烟草以及模式植物拟南芥为研究材料,克隆与作物发育、抗逆性等密切相关的功能基因,探讨这些基因的表达模式及其调控机制,研究其在作物遗传改良上的利用价值,获得拥有我国自己专利或知识产权的基因,为生物技术育种提供基因资源。2.基因表达调控元件的鉴定与应用:
人为控制外源基因在转基因作物的特定器官、特定时期表达,必须依靠组织专一型启动子、发育诱导型启动子和其它基因表到调控元件。本方向主要研究各类启动子的表达调控机制和应用,染色质重塑与基因表达,核基质结合序列MAR(matrix attachment region)对转基因表达的调控机制与应用。主要论文
在《
Molecular Cell
》[3](影响因子14.178
)、《 Neuclear Acids Research
》、《 Plant
Physiology》、《 New Phytologist
》、《 中国科学
》、《 科学通报
》等国内外著名学术刊物上发表论文170多篇。1、Zheng CC, Porat R, Lu P, O’Neill SD. PNZIP is a novel mesophyll-specific cDNA that is regulated by phytochrome and a circadian rhythm and encodes a protein with a leucine zipper motif. Plant Physiology, 1998, 116:27~35
2、Zheng CC, Bui AQ, O’Neill SD. Abundance of an mRNA encoding a HMG DNA-binding protein is regulated by light and an endogenous rhythm. Plant Molecular Biology. 1993, 23:813~823
3、张可伟,郑成超(通讯作者)。强MAR的分离及体外功能鉴定。科学通报,2002,47(20):1572- 1577
4、杨宇涛,郑成超(通讯作者)。一个光合组织特异表达强启动子的分离及功能分析。中国科学,2003,33(4):298-306.
5、李宏,郑成超(通讯作者)。6个植物MARs序列的ARS功能鉴定与分析。科学通报,2003,48(24):2544- 2548
6、Ning Liu, Cheng-Chao Zheng(通讯作者), NTZIP antisense plants show reduced chlorophyll levels, Plant Physiology and Biochemistry. 2004,42(4):321-327
7、Changai Wu, Zheng Chengchao(通讯作者). The cotton GhNHX1 gene encoding a novel putative tonoplast Na+/H+ antiporter plays an important role in salt stress. Plant and Cell Physiology, 2004,45(5): 489-496
8、Hai-Yan Li, Cheng-Chao Zheng(通讯作者). Colonization by the Arbuscular Mycorrhizal Fungus Glomus versiforme Induces a Defense Response Against the Root-knot Nematode Meloidogyne incognita in the Grapevine (Vitis amurensis Rupr.), Which Includes Transcriptional Activation of the Class III Chitinase Gene VCH3. Plant and Cell Physiology, 2006, 47(1): 154–163
9、Xiao Wang, Chengchao Zheng(通讯作者). Isolation and purification of honokiol and magnolol from cortex magnoliae officinalis by high-speed counter-current chromatography. Journal of chromatography A. 2004, 1036(2):171-175.
10、Xiao Wang, Chengchao Zheng(通讯作者) An efficient new method for extraction, separation and purification of psoralen and isopsoralen from Fructus Psoraleae by supercritical fluid extraction and high-speed counter-current chromatography。Journal of chromatography A. 2004,.1055:135-140
11、Xiao Wang, Chengchao Zheng(通讯作者). Application of preparative high-speed counter-current chromatography for separation and purification of arctiin from Fructus Arctii, Journal of chromatography A. 2004, 1063: 247-251
12、Hua Xue, Cheng-Chao Zheng(通讯作者), TM2, a novel strong matrix attachment region isolated from tobacco, increases transgene expression in transgenic rice calli and plants. Theoretical and Applied Genetics. 2005, 110:620-627
13、Hongxin Zhang and Cheng-Chao Zheng(通讯作者).Expression and characterization of Helicobacter pylori heat-shock protein A (HspA) protein in transgenic tobacco (Nicotiana tabacum) plants. Biotechnology and Appllied Biochemistry. 2006,43, 33–38
14、 Da-Peng Shan, Jin-Guang Huang, Yu-Tao Yang, Ying-Hui Guo and
Cheng-Chao Zheng*
. Cotton GhDREB1 increases plant tolerance to low temperature and is negatively regulated by gibberellic acid. New Phytologist
2007. 176: 70–8115、Meng-Meng Zhanga, Lu-Sha Ji, Hua Xue, Yu-Tao Yang, Chang-Ai Wu and
Cheng-Chao Zheng*
. High transformation frequency of tobacco and rice via Agrobacterium-mediated gene transfer by flanking a tobacco matrix attachment region Physiologia Plantarum
2007.129: 644–651.16、Dong Wang, Yinghui Guo, Changai Wu, Guodong Yang, Yingying Li and
Chengchao Zheng*
. Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice. BMC Genomics
2008, 9:4417、Hanhua Liu, Xin Tian, Yanjie Li, Changai Wu and
Chengchao Zheng*
.Microarray-based analysis of stress-regulated microRNAs in Arabidopsis thaliana. RNA
2008, 14: 836-84318、 Xin Huang · Wei Zhu · Silan Dai · Shupeng Gai ·Guosheng Zheng ·
Chengchao Zheng
*. The involvement of mitochondrial phosphate transporter in accelerating bud dormancy release during chilling treatment of tree peony (Paeonia suVruticosa). Planta
2008, 228(4):545-5219、Xiyan Yu, Xiufeng Wang, Wenqian Zhang, Tingting Qian, Guimin Tang, Yankui Guo,
Chengchao Zheng
*. Antisense Suppression of an Acid Invertase Gene (MAI1) in Muskmelon Alters Plant Growth and Fruit Development. Journal of Experimental Botany
.2008, 59(11):2969-77.20、Jiedao Zhang, Longtao Lu, Lusha Ji, Guodong Yang,
Chengchao Zheng
*. Functional characterization of a tobacco matrix attachment region-mediated enhancement of transgene expression. Transgenic Research.
2009, 18:377-38521、 Hongxin Zhang and
Cheng-Chao Zheng
* Oral immunogenicity and protective efficacy in mice of a carrot-derived vaccine candidate expressing UreB subunit againstHelicobacter pylori.Protein Expression and Purification
. 2009, 69:127-13122、Tongtong Xue, Xinzheng Li, Wei Zhu, Changai Wu, Guodong Yang, and
Chengchao Zheng*
. Cotton metallothionein GhMT3a, a reactive oxygen species scavenger, increased tolerance against abiotic stress in transgenic tobacco and yeast. Journal of Experimental Botany
.2009, 60: 339-34923、 Ying-Hui Guo, Yue-Ping Yu, Dong Wang, Chang-Ai Wu, Guo-Dong Yang, Jin-Guang Huang and
Cheng-Chao Zheng*
. GhZFP1, a novel CCCH-type zinc finger protein from cotton, enhances salt stress tolerance and fungal disease resistance in transgenic tobacco by interacting with GZIRD21A and GZIPR5. New Phytologist
2009, 183: 62–7524、Yu-Tao Yang, Yan-Li Yu, Guo-Dong Yang, Jie-Dao Zhang and
Cheng-Chao Zheng*
, Tissue-specific expression of the PNZIP promoter is mediated by combinatorial interaction of different cis-elements and a novel ranscriptional factor. Nucleic Acids Research
2009, 37(8):2630–264425、Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu and
Cheng-Chao Zheng*
.GhDREB1enhances abiotic stress tolerance, delays GA-mediated development and represses cytokinin signaling in transgenic Arabidopsis. Plant, Cell & Environment
, 2009, 32, 1132–114526、YanLi Yu, YanZe Li, LingLi Li, JinXing Lin,
ChengChao Zheng*
Overexpression ofPwTUA1, a pollen-specific tubulin gene, increases pollen tube elongation by altering the distribution of α-tubulin and promoting vesicle transport. Journal of Experimental Botany
,
2009, 60(9):2737-4927、 Yanjie Li, Yaru Fu, Lusha Ji, Changai Wu,
Chengchao Zheng*.
Characterization and expression analysis of the Arabidopsis mir169 family. Plant Science
2010,178: 271-28028、Jin-Guang Huang, Mei Yang, Pei Liu, Guo-Dong Yang, Chang-Ai Wu,
Cheng-Chao Zheng*.
Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis. Gene.
2010, 451:38-4429、Dongmei Xi, Wushuang Liu, Guodong Yang, Changai Wu,
Cheng-chao Zheng*
. Seed-specific overexpression of antioxidant genes in Arabidopsis enhances oxidative stress tolerance during germination and early seedling growth. Plant Biotechnology Journal,
2010, 8:796-806.30、 Hao Huan, Sheng-Dong Qi, Fang Qi, Chang-Ai Wu, Guo-Dong Yang and
Cheng-Chao Zheng*
. NtKTI1, a Kunitz trypsin inhibitor with antifungal activity from Nicotiana tabacum, plays an important role in tobacco’s defense response. FEBS Journal
2010, 277:4076-4088 .
31、Yanjie Li, Yaru Fu, Jinguang Huang, Changai Wu and
Chengchao Zheng*
Insight into the transcriptional regulation during the early development of the maize brace root. FEBS Journal
2010